Lewis rat NLRP1 inflammasome activation is mediated by three Toxoplasma gondii dense granule proteins
Yifan Wang, Kimberly M. Cirelli, Patricio D.C. Barros, Lamba Omar Sangaré, Vincent Butty, Musa A. Hassan, Patricia Pesavento, Asli Mete, Jeroen P.J. Saeij
This study identifies three Toxoplasma gondii dense granule proteins, GRA35, GRA42, and GRA43, as essential for NLRP1 inflammasome activation in Lewis rat macrophages and parasite in vivo fitness.
bioRxiv · Jul 31, 2018 · PreprintMicrobiology