Yifan Wang

High-Dimensional Immunophenotyping Identifies Circulating Immune Signatures Associated with FeNO-Defined Asthma Phenotypes

This study identifies distinct systemic immune signatures in asthma patients based on FeNO levels using high-dimensional immunophenotyping.

Sensory cortical disinhibition is required for long-term fear memory in humans

This study uses HD-tACS and neural decoding to show that sensory cortical disinhibition is necessary for long-term fear memory in humans.

The neural control of infanticide and parental behaviors in male mice

The paper identifies a shared neural circuit in male mice that controls pup-directed behaviors, with sex differences in cell activity balance influencing infanticide and paternal care.

Multiomic Spatial Imaging Assay (MSIA) -- A High-plex In Situ Detection Method for mRNAs, Proteins, and Protein-Protein Interactions using Manual And Semi-Automated Workflows

The paper introduces MSIA, a multiomic spatial imaging method for detecting mRNAs, proteins, and protein interactions, and demonstrates its application in Parkinson's Disease research.

The metabolic enzyme GYS1 condenses with NONO/p54nrb in the nucleus to spatiotemporally regulate glycogenesis and myogenic differentiation

This study shows that GYS1 forms nuclear condensates with NONO/p54nrb to regulate glycogenesis and myogenic differentiation.

BRCA1 secondary splice-site mutations drive exon-skipping and PARP inhibitor resistance

This study identifies secondary splice-site mutations in BRCA1 that drive exon skipping and PARP inhibitor resistance in ovarian and breast cancer.

Lewis rat NLRP1 inflammasome activation is mediated by three Toxoplasma gondii dense granule proteins

This study identifies three Toxoplasma gondii dense granule proteins, GRA35, GRA42, and GRA43, as essential for NLRP1 inflammasome activation in Lewis rat macrophages and parasite in vivo fitness.