Orthogonal CRISPR screens and human liver chimeric mice identify hepatitis B virus host factors
Catherine A. Freije, Georgios Dangas, Antonis Athanasiadis, Evgenia Moschogianni, Madeleine K Sanders, Allan Henrique Depieri Cataneo, Chloe K. Boehm, Maria Bousali, Dar-Yin Li, Sooyoung Lee, Guillaume Cornelis, Gary Lo, Leah B. Soriaga, Amalio Telenti, Julia di Iulio, , Eleftherios Michailidis
The paper identifies HBV host factors using CRISPR screens and human liver chimeric mice, finding that EXOC1 is antiviral and ZCCHC14 is proviral.
bioRxiv · Jul 24, 2026 · PreprintMicrobiology