Position-sensing established duringcompaction dictates cell fate in themammalian embryo
Christophe Royer, Karolis Leonavicius, Annemarie Kip, Deborah Fortin, Kirtirupa Nandi, Anna Vincent, Celine Jones, Tim Child, Kevin Coward, Chris Graham, Shankar Srinivas
The paper shows that blastomere position during early embryogenesis influences YAP localization through apicobasal polarity and PKC signaling, affecting cell fate decisions.
bioRxiv · Dec 3, 2019 · PreprintDevelopmental Biology