Isoforms of the TAL1 transcription factor have different roles in hematopoiesis and cell growth
Aveksha Sharma, Shani Mistriel-Zerbib, Rauf Ahmad Najar, Eden Engal, Mercedes Bentata, Nadeen Taqatqa, Sara Dahan, Klil Cohen, Shiri Jaffe‐Herman, Ophir Geminder, Mai Baker, Yuval Nevo, Inbar Plaschkes, Gillian Kay, Yotam Drier, , Maayan Salton
This study investigates the roles of TAL1 isoforms in hematopoiesis and cell growth, finding that TAL1-short promotes apoptosis and can act as a tumor suppressor.
PLoS Biology · Jun 28, 2023Peer-reviewedMolecular Biology