Identification of Novel Inhibitors of JEV RdRp as Potent Antiviral Drugs: Targeting NS5-NS3 Protein Interaction
Preeti Mishra, Shriyanshi Mishra, Gaurava Srivastava, Km. Archana, Mohammad Imran Siddiqi, Sourav Haldar, Raj Kamal Tripathi
This study identifies DSHS00151 as a potent inhibitor of JEV NS5-NS3 interaction, showing dose-dependent antiviral effects with IC50 values lower than CD10712.
bioRxiv · Sep 28, 2026 · PreprintPathology