Wnt signaling mediates acquisition of blood-brain barrier properties in naïve endothelium derived from human pluripotent stem cells
Benjamin D. Gastfriend, Hideaki Nishihara, Scott Glen Canfield, Koji L Foreman, Britta Engelhardt, Sean P. Palecek, Eric V Shusta
This study shows that activating Wnt signaling in human pluripotent stem cell-derived naive endothelial progenitors promotes the acquisition of blood-brain barrier properties.
eLife · Nov 10, 2021Peer-reviewedNeuroscience