Britta Engelhardt

This study investigates whether methylglyoxal (MGO) crosses the blood-brain barrier (BBB) in vivo and affects BBB permeability in vitro, finding no significant MGO passage or barrier disruption.

This study shows that vitamin D reduces effector T-cell migration across the blood-brain barrier while preserving regulatory T-cell entry, potentially benefiting multiple sclerosis patients.

The paper uses CITE-seq to analyze B cells from vitamin D-treated MS patients, identifying NF-kB pathway inhibition as a potential mechanism for vitamin D's protective effects.

This study characterizes a novel MAGL inhibitor in a mouse model and human cells, showing its expression in neurovascular unit cells but no effect on blood-brain barrier permeability or cytokine production.

This study shows that activating Wnt signaling in human pluripotent stem cell-derived naive endothelial progenitors promotes the acquisition of blood-brain barrier properties.

This paper identifies CD31 as the receptor for Clostridium perfringens β-toxin, explaining its cell type specificity and toxicity.