Author

Benjamin D. Gastfriend

University of Wisconsin–MadisonORCID 0000-0002-4677-1455Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Eric V. ShustaiD· 2 shared Scott Glen CanfieldiD· 2 shared Sean P. PalecekiD· 2 shared Abdel G. ElkahlouniD· 1 shared Anna M. BagnelliD· 1 shared Avindra NathiD· 1 shared Britta EngelhardtiD· 1 shared Drew Richards· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersNeuroscience

Eric V. ShustaORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 20, 2025

3D organoids containing endothelial and neural cells generation by serial inductions of differentiation on human iPSC-derived embryoid bodies

Tongguang Wang, Anna M. Bagnell, Valerie McDonald…·Avindra Nath

This paper develops 3D brain organoids with endothelial and neural cells using sequential differentiation of iPSC-derived embryoid bodies, showing enhanced angiogenesis and SARS-CoV-2 receptor expression.

1 citation

humanscRNA-seq

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NeuroscienceeLifePeer-reviewedNov 10, 2021

Wnt signaling mediates acquisition of blood-brain barrier properties in naïve endothelium derived from human pluripotent stem cells

Benjamin D. Gastfriend, Hideaki Nishihara, Scott Glen Canfield…·Eric V Shusta

This study shows that activating Wnt signaling in human pluripotent stem cell-derived naive endothelial progenitors promotes the acquisition of blood-brain barrier properties.

86 citationstop 3%

humanbulk RNA-seq

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NeuroscienceScience AdvancesPeer-reviewedMar 1, 2019

Human pluripotent stem cell-derived brain pericyte-like cells induce blood-brain barrier properties

Matthew J. Stebbins, Benjamin D. Gastfriend, Scott Glen Canfield…·Eric V. Shusta

The paper generates human pluripotent stem cell-derived brain pericyte-like cells that induce blood-brain barrier properties in endothelial cells and form an isogenic NVU model.

195 citationstop 1%

humanbulk RNA-seq

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