Formylation facilitates the reduction of oxidized initiator methionines
Ruiyue Tan, Margaret Hoare, Philip Bellomio, Sarah Broas, Konttessa Camacho, Kyle Swovick, Kevin A. Welle, Jennifer R. Hryhorenko, Sina Ghaemmaghami
This study shows that formylation of initiator methionines enhances their enzymatic reduction and mitigates oxidation-related misprocessing.
bioRxiv · Feb 6, 2024Biochemistry