BiochemistryJournal of Peptide SciencePeer-reviewed
Targeting phosphoRab-RILPL Interactions as a Strategy to Downregulate Pathogenic LRRK2 in Parkinson's Disease
Krista K. Alexander, Yahaira Naaldijk, Rachel Fasiczka…·Eileen J. Kennedy
This paper demonstrates that constrained peptides mimicking phosphorylated Rab8 can block RILPL interactions and restore ciliogenesis and centrosomal cohesion defects in cells with mutant LRRK2.
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