Author

Kristina M Cook

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Bernadette Kerr· 1 shared Nalin Kataria· 1 shared Samantha S. Zaiter· 1 shared Shelli McAlpine· 1 shared

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2019-2019 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperCancer Biology

Bernadette Kerr

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintJan 24, 2019

C-terminal HSP90 Inhibitors Block the HSP90:HIF-1a Interaction and Inhibit the Cellular Hypoxic Response

Nalin Kataria, Bernadette Kerr, Samantha S. Zaiter…·Kristina M Cook

This study shows C-terminal HSP90 inhibitors block HIF-1 stabilization under hypoxia, leading to HIF-1 degradation and reduced hypoxic gene expression in colorectal cancer cells.

DOI 10.1101/521989

humanbulk RNA-seq

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