Systematic identification and characterization of regulators of aryl hydrocarbon receptor signaling
Manasvi Verma, Kushaal Desai, Yufang Ding, Xingren Wang, Minwoo Bae, Seth Rakoff-Nahoum, Emily P. Balskus, Michael Andrew Fischbach, Marco Jost
This study identifies regulators of AHR signaling in hepatocytes using CRISPR screening, revealing novel mechanisms and cell-type-specific components for therapeutic targeting.
bioRxiv · Sep 15, 2025 · PreprintGenomics