Author

L. A. Aaltonen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:comparative / phylogenetic analysis· 1 Assay:DNA methylation· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

A. Iftekhar· 1 shared A. Sacchetti· 1 shared B. A. Bowman· 1 shared B. van der Steen· 1 shared D. Seinstra· 1 shared F. Battistini· 1 shared H. Berger· 1 shared J. Choi· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. Iftekhar

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The origin of intestinal cancer in the context of inflammation

M. P. Verhagen, R. Joosten, M. Schmitt, N. Valimaki, A. Sacchetti, K. Rajamaki, J. Choi, P. Procopio, S. Silva, B. van der Steen, T. P. P. van den Bosch, D. Seinstra, M. Doukas, L. H. Augenlicht, L. A. Aaltonen, R. Fodde

The paper shows that secretory cell lineages, not stem cells, can trigger tumor formation in the context of inflammation and Western-style diets, which are major colon cancer risk factors.

bioRxiv · Oct 2, 2023 · PreprintCancer Biology

Colibactin DNA damage signature indicates causative role in colorectal cancer

P. J. Dziubanska Kusibab, H. Berger, F. Battistini, B. A. Bowman, A. Iftekhar, R. Katainen, N. Crosetto, M. Orozco, L. A. Aaltonen, T. F. Meyer

The paper identifies a mutational signature caused by colibactin in human colorectal cancers.

bioRxiv · Oct 25, 2019 · PreprintMicrobiology