Dynamic intestinal stem cell plasticity and lineage remodeling 1 by a nutritional environment relevant to human risk for tumorigenesis
J. Choi, X. Zhang, W. Li, M. Houston, K. Peregrina, R. Dubin, K. Ye, L. Augenlicht
This study shows that a nutrient-rich diet reprograms intestinal stem cells and lineages, promoting tumorigenesis by altering stem cell function and inducing chronic inflammation.
bioRxiv · Mar 17, 2022Cancer Biology