Author

M. Houston

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1

Frequent Co-Authors

J. Choi· 2 shared K. Ye· 2 shared W. Li· 2 shared X. Zhang· 2 shared D. M. Huffman· 1 shared K. Peregrina· 1 shared L. Augenlicht· 1 shared L. H. Augenlicht· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

J. Choi

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Intestinal stem cell aging at single-cell resolution: functional perturbations alter cell developmental trajectory reversed by gerotherapeutics

J. Choi, M. Houston, R. Wang, K. Ye, W. Li, X. Zhang, D. M. Huffman, L. H. Augenlicht

This study uses single-cell RNA sequencing to show that aging impairs intestinal stem cell maturation, which is reversed by metformin and rapamycin.

bioRxiv · Aug 31, 2022 · PreprintCell Biology

Dynamic intestinal stem cell plasticity and lineage remodeling 1 by a nutritional environment relevant to human risk for tumorigenesis

J. Choi, X. Zhang, W. Li, M. Houston, K. Peregrina, R. Dubin, K. Ye, L. Augenlicht

This study shows that a nutrient-rich diet reprograms intestinal stem cells and lineages, promoting tumorigenesis by altering stem cell function and inducing chronic inflammation.

bioRxiv · Mar 17, 2022Cancer Biology