Characterization of the dynamic resting state of a pentameric ligand-gated ion channel by cryo-electron microscopy and simulations
U. Rovsnik, Y. Zhuang, L. Axelsson, B. O. Forsberg, V. T. Lim, M. Carroni, C. Blau, R. J. Howard, E. Lindahl
The paper uses cryo-EM and simulations to characterize the resting and activating states of GLIC, revealing structural changes and energy landscape dynamics.
bioRxiv · Jun 19, 2020 · PreprintBiophysics