Human cytomegalovirus UL7, miR-US5-1 and miR-UL112-3p inactivation of FOXO3a protects CD34+ hematopoietic progenitor cells from apoptosis
M. H. Hancock, L. B. Crawford, W. Perez, H. M. Struthers, J. Mitchell, P. Caposio
This study identifies HCMV proteins and miRNAs that inhibit FOXO3a to prevent apoptosis in CD34+ hematopoietic progenitor cells, aiding viral latency.
bioRxiv · Sep 28, 2020Microbiology