Author

L. Buyachuihan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

M. Grininger· 2 shared C. S. Schelhas· 1 shared M. Klaus· 1 shared Y. Zhao· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 4 mutual co-author links

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2 shared papersBiochemistry

M. Grininger

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2 papers

Recent·Most cited

Docking Domain Engineering in a Modular Polyketide Synthase and its Impact on Structure and Function

L. Buyachuihan, Y. Zhao, C. S. Schelhas, M. Grininger

This study engineers docking domains in modular PKSs to couple polypeptides, showing that high-affinity interactions can improve synthesis but may reduce rates, with efficiency recovery through hinge regions.

bioRxiv · Feb 3, 2023Biochemistry

The Ketosynthase Domain Constrains the Design of Polyketide Synthases

M. Klaus, L. Buyachuihan, M. Grininger

This study identifies bottlenecks in chimeric modular PKSs and proposes guidelines for improving their efficiency through targeted mutations in the ketosynthase domain.

bioRxiv · Jan 23, 2020Biochemistry