Author

L. Casciola-Rosen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Rosen· 2 shared A. A. Shah· 1 shared A. Baer· 1 shared A. Rosenberg· 1 shared B. Antiochos· 1 shared C. Mecoli· 1 shared D. W. Goldman· 1 shared J. Li· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

A. Rosen

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2 papers

Recent·Most cited

ImmunologyeLifePeer-reviewedMay 24, 2022

The DNA sensors AIM2 and IFI16 are NET-binding SLE autoantigens

B. Antiochos, P. Fenaroli, A. Rosenberg…·A. Rosen

The paper identifies AIM2 and IFI16 as autoantigens in SLE that bind NETs, leading to DNase-resistant structures that promote sustained IFN signaling.

DOI 10.7554/elife.72103

humanproteomics

𝕏 PostBluesky

ImmunologybioRxivApr 21, 2017

Estimating Autoantibody Signatures To Detect Autoimmune Disease Patient Subsets

Z. Wu, L. Casciola-Rosen, A. A. Shah…·S. L. Zeger

This paper develops a Bayesian hierarchical model to improve autoantibody signature detection by aligning and dewarping autoradiograms, enhancing subset identification in autoimmune diseases.

DOI 10.1093/biostatistics/kxx061

humanproteomics

𝕏 PostBluesky