Author

L. Craciun

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

C. Maenhaut· 3 shared M. Tarabichi· 3 shared D. Larsimont· 2 shared F. Libert· 2 shared G. Andry· 2 shared J. E. Dumont· 2 shared V. Detours· 2 shared A. Antoniou· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersCancer Biology

C. Maenhaut

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3 papers

Recent·Most cited

Idiosyncratic and generic single nuclei and spatial transcriptional patterns in papillary and anaplastic thyroid cancers

A. Tourneur, J. Rodrigues Vitoria, M. Saiselet, L. Craciun, D. Larsimont, A. Lefort, F. Libert, C. Maenhaut, S. Costagliola, M. Tarabichi, M. Romitti, V. Detours

This study uses single nuclei RNA-seq and spatial transcriptomics to analyze transcriptional patterns in papillary and anaplastic thyroid cancers, revealing idiosyncratic and generic transcriptional variations and EMT-related features.

bioRxiv · Feb 15, 2024 · PreprintCancer Biology

CDK4 phosphorylation status and rational use for combining CDK4/6 and BRAF/MEK inhibition in advanced thyroid carcinomas

J. M. Pita, E. Raspe, K. Coulonval, M. Decaussin-Petrucci, M. Tarabichi, G. Dom, F. Libert, L. Craciun, G. Andry, L. Wicquart, E. Leteurtre, C. Tresallet, L. A. Marlow, J. A. Copland, C. Durante, , P. P. Roger

This study shows that CDK4 phosphorylation status predicts response to CDK4/6 inhibitors in thyroid carcinomas and supports combining them with BRAF/MEK inhibitors to prevent resistance.

bioRxiv · Jun 5, 2023Cancer Biology

Distinctive desmoplastic 3D morphology associated with BRAFV600E in papillary thyroid cancers

M. Tarabichi, A. Antoniou, S. Le Pennec, D. Gacquer, N. de Saint Aubain, L. Craciun, T. Cielen, I. Laios, D. Larsimont, G. Andry, J. E. Dumont, C. Maenhaut, V. Detours

The paper describes a distinctive 3D morphology in BRAFV600E-mutated papillary thyroid cancers where tumor cells form a sparse mesh within a proliferative stroma, challenging traditional tumor growth models.

bioRxiv · Jul 6, 2017Cancer Biology