Author

A. Lefort

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1

Frequent Co-Authors

F. Libert· 4 shared M. Leprovots· 2 shared M.-I. Garcia· 2 shared A. Delchambre· 1 shared A. E. Cobham· 1 shared A. Hadefi· 1 shared A. Nonclercq· 1 shared A. Tourneur· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersCell Biology

F. Libert

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Idiosyncratic and generic single nuclei and spatial transcriptional patterns in papillary and anaplastic thyroid cancers

A. Tourneur, J. Rodrigues Vitoria, M. Saiselet, L. Craciun, D. Larsimont, A. Lefort, F. Libert, C. Maenhaut, S. Costagliola, M. Tarabichi, M. Romitti, V. Detours

This study uses single nuclei RNA-seq and spatial transcriptomics to analyze transcriptional patterns in papillary and anaplastic thyroid cancers, revealing idiosyncratic and generic transcriptional variations and EMT-related features.

bioRxiv · Feb 15, 2024 · PreprintCancer Biology

Starvation resistant cavefish reveal conserved mechanisms of starvation-induced hepatic lipotoxicity

M. Pozo-Morales, A. E. Cobham, C. Centola, M. C. McKinney, P. Liu, C. Perazzolo, A. Lefort, F. Libert, H. Bai, N. Rohner, S. P. Singh

The paper identifies FATP2 as a conserved target for preventing starvation-induced liver atrophy by reducing fatty acid uptake in cavefish and other species.

bioRxiv · Jan 10, 2024 · PreprintCell Biology

THE OLFACTORY RECEPTOR Olfr78 REGULATES DIFFERENTIATION OF ENTEROCHROMAFFIN CELLS IN THE MOUSE COLON

M.-I. Garcia, G. Dinsart, M. Leprovots, A. Lefort, F. Libert, Y. Quesnel, A. Veiten, G. Vassart, S. Huysseune, M. Parmentier

This study shows that the olfactory receptor Olfr78 regulates enterochromaffin cell differentiation in the mouse colon, affecting gut homeostasis and microbiota balance.

bioRxiv · Apr 19, 2023 · PreprintCell Biology

The bacterial genetic determinants of Escherichia coli capacity to cause bloodstream infections in humans

J. Burgaya, J. Marin, G. Royer, B. Condamine, B. Gachet, O. Clermont, F. Jaureguy, C. Burdet, A. Lefort, V. de Lastours, E. Denamur, M. Galardini, F. Blanquart, The Colibafi/Septicoli Group, The COLIVILLE Group

This study identifies genetic determinants of Escherichia coli's ability to cause bloodstream infections using genomic and machine learning analyses of clinical isolates.

bioRxiv · Dec 31, 2022 · PreprintMicrobiology

COLD ATMOSPHERIC PLASMA DIFFERENTIALLY AFFECTS CELL RENEWAL AND DIFFERENTIATION OF STEM CELLS AND APC-DEFICIENT-DERIVED TUMOR CELLS IN INTESTINAL ORGANOIDS

A. Hadefi, M. Leprovots, M. Thulliez, O. Bastin, A. Lefort, F. Libert, A. Nonclercq, A. Delchambre, F. Reniers, J. Deviere, M.-I. Garcia

This study examines how cold atmospheric plasma affects stem cells and tumor cells in intestinal organoids, finding differential responses with tumor cells showing higher resistance.

bioRxiv · Oct 13, 2021Cell Biology