Author

S. Costagliola

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

M. Romitti· 3 shared A. Tourneur· 2 shared V. Detours· 2 shared A. A. Schiavo· 1 shared A. L. Maia· 1 shared A. Lefort· 1 shared B. Aganahi· 1 shared B. d. F. da Fonseca· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

M. Romitti

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Idiosyncratic and generic single nuclei and spatial transcriptional patterns in papillary and anaplastic thyroid cancers

A. Tourneur, J. Rodrigues Vitoria, M. Saiselet, L. Craciun, D. Larsimont, A. Lefort, F. Libert, C. Maenhaut, S. Costagliola, M. Tarabichi, M. Romitti, V. Detours

This study uses single nuclei RNA-seq and spatial transcriptomics to analyze transcriptional patterns in papillary and anaplastic thyroid cancers, revealing idiosyncratic and generic transcriptional variations and EMT-related features.

bioRxiv · Feb 15, 2024 · PreprintCancer Biology

The highly and perpetually upregulated thyroglobulin gene is a hallmark of functional thyrocytes

S. Ullrich, S. Leidescher, Y. Feodorova, K. Thanisch, J.-B. Fini, B. Kaspers, F. Weber, B. Markova, D. Fuehrer, M. Romitti, S. Krebs, H. Blum, H. Leonhardt, S. Costagliola, H. Heuer, I. Solovei

The paper identifies thyroglobulin gene (Tg) as a permanently upregulated gene in thyrocytes across vertebrates, providing insights into mechanisms of sustained transcriptional activation.

bioRxiv · Jun 23, 2023Cell Biology

Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of Braf-mutated thyroid cancer organoids

H. Lasolle, A. A. Schiavo, A. Tourneur, P. Gillotay, B. d. F. da Fonseca, L. Ceolin, O. Monestier, B. Aganahi, L. Chomette, M. M. L. Kizys, L. Haenebalcke, T. Pieters, S. Goossens, J. Haigh, V. Detours, , M. Romitti

This study uses thyroid organoids to show that combining MAPK and PI3K inhibitors can reverse dedifferentiation in Braf-mutated thyroid cancer cells.

bioRxiv · Mar 30, 2023 · PreprintCancer Biology