Author

L. E. Gentles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

J. D. Bloom· 3 shared A. J. Greaney· 2 shared A. N. Loes· 2 shared K. H. Crawford· 2 shared H. Wan· 1 shared H. Y. Chu· 1 shared K. D. Malone· 1 shared M. Eichelberger· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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3 shared papersMicrobiology

J. D. Bloom

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Author profile →

3 papers

Recent·Most cited

The SARS-CoV-2 mRNA-1273 vaccine elicits more RBD-focused neutralization, but with broader antibody binding within the RBD

A. J. Greaney, A. N. Loes, L. E. Gentles, K. H. Crawford, T. N. Starr, K. D. Malone, H. Y. Chu, J. D. Bloom

The paper compares the specificity of antibodies from the mRNA-1273 vaccine and natural infection, finding vaccine antibodies are more RBD-focused but have broader epitope coverage within the RBD.

bioRxiv · Apr 14, 2021Microbiology

Attenuated influenza virions expressing the SARS- CoV-2 receptor-binding domain induce neutralizing antibodies in mice

A. N. Loes, L. E. Gentles, A. J. Greaney, K. H. Crawford, J. D. Bloom

This paper describes an influenza-based vaccine for SARS-CoV-2 that induces neutralizing antibodies in mice comparable to natural infection.

bioRxiv · Aug 12, 2020Microbiology

Antibody neutralization of an influenza virus that uses neuraminidase for receptor binding

L. E. Gentles, H. Wan, M. Eichelberger, J. D. Bloom

This study shows that anti-NA antibodies can neutralize influenza viruses that use NA for receptor binding, enabling sensitive detection and escape mutant selection.

bioRxiv · May 8, 2020Microbiology