Distinct photooxidation-induced cell death pathways lead to selective killing of human breast cancer cells
A. F. dos Santos, A. Inague, G. S. Arini, L. F. Terra, R. A. M. Wailemann, A. C. P. C. Pimentel, M. Y. Yoshinaga, R. R. S. R. Silva, D. Severino, D. R. Q. de Almeida, V. M. Gomes, A. Bruni-Cardoso, W. R. Terra, S. Miyamoto, M. S. Baptista, L. Labriola
This study identifies distinct photooxidation-induced cell death pathways in human breast cancer cells, showing MB-PDT selectively kills tumorigenic cells through ferroptosis and necroptosis.
bioRxiv · Jun 25, 2020Cancer Biology