Author

A. F. dos Santos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

G. S. Arini· 2 shared L. Labriola· 2 shared A. Bruni-Cardoso· 1 shared A. C. P. C. Pimentel· 1 shared A. Florez· 1 shared A. Inague· 1 shared A. Przybylla· 1 shared A. Schulze· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

G. S. Arini

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Selenocysteine metabolism is a targetable vulnerability in MYCN-amplified cancers

H. Alborzy, Z. Chen, U. Yildiz, F. Porto- Freitas, F. C. E. Vogel, J. Varga, J. Batani, C. Bartenhagen, W. Schmitz, G. Buechel, B. Michalke, J. Zheng, S. Meierjohann, E. Girardi, E. Espinet, , J. P. Friedmann Angeli

This study identifies LRP8 as a targetable vulnerability in MYCN-amplified neuroblastoma by showing its role in selenocysteine import and resistance to ferroptosis.

bioRxiv · May 17, 2022 · PreprintCancer Biology

SARS-CoV-2 activates ER stress and Unfolded protein response

L. Rosa-Fernandes, L. C. Lazari, J. Macedo-da-Silvia, V. d. M. Gomes, R. R. G. Machado, A. F. dos Santos, D. B. Araujo, J. V. P. Coutinho, G. S. Arini, C. B. Angeli, E. E. de Souza, C. Wrenger, C. R. F. Marinho, D. B. L. Oliveira, E. L. Durigon, , G. Palmisano

This study shows SARS-CoV-2 activates ER stress and UPR pathways in infected cells, which are essential for viral replication and may be targets for antiviral drugs.

bioRxiv · Jun 21, 2021 · PreprintBiochemistry

Distinct photooxidation-induced cell death pathways lead to selective killing of human breast cancer cells

A. F. dos Santos, A. Inague, G. S. Arini, L. F. Terra, R. A. M. Wailemann, A. C. P. C. Pimentel, M. Y. Yoshinaga, R. R. S. R. Silva, D. Severino, D. R. Q. de Almeida, V. M. Gomes, A. Bruni-Cardoso, W. R. Terra, S. Miyamoto, M. S. Baptista, L. Labriola

This study identifies distinct photooxidation-induced cell death pathways in human breast cancer cells, showing MB-PDT selectively kills tumorigenic cells through ferroptosis and necroptosis.

bioRxiv · Jun 25, 2020Cancer Biology