Author

L. Freire-de-Lima

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

E. J. Salustiano· 2 shared J. O. Previato· 2 shared K. M. da Costa· 2 shared L. Mendonca-Previato· 2 shared R. C. Valente· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersCancer Biology

E. J. Salustiano

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2 papers

Recent·Most cited

Inhibition of glycosphingolipid biosynthesis reverts multidrug resistance by differential modulation of ABC transporters on chronic myeloid leukemias

E. J. Salustiano, K. M. da Costa, L. Freire-de-Lima, L. Mendonca-Previato, J. O. Previato

This study shows that inhibiting glycosphingolipid biosynthesis reduces multidrug resistance in chronic myeloid leukemias by modulating ABC transporter activity.

Journal of Biological Chemistry · May 1, 2020Peer-reviewedCancer Biology

Thiol efflux mediated by an ABCC-like transporter participates for Trypanosoma cruzi adaptation to environmental and chemotherapeutic stresses

K. M. da Costa, E. J. Salustiano, R. C. Valente, L. Freire-de-Lima, L. Mendonca-Previato, J. O. Previato

This study identifies an ABCC-like transporter in Trypanosoma cruzi that mediates thiol efflux, contributing to stress resistance and adaptation to chemotherapeutic agents.

bioRxiv · Mar 26, 2020 · PreprintMicrobiology