Author

L. G. Morosi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

F. Benvenuti· 3 shared G. M. Piperno· 3 shared R. Amadio· 3 shared S. Joshi· 3 shared S. Vodret· 2 shared A. Bardelli· 1 shared C. Volponi· 1 shared D. Lazarevic· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

F. Benvenuti

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

DCs targeted therapy expands CD8 T cell responses to bona-fide neoantigens in lung tumors

L. Lopez, L. G. Morosi, F. La Terza, P. Bourdely, G. Rospo, R. Amadio, G. M. Piperno, V. Russo, C. Volponi, S. Vodret, S. Joshi, F. Giannese, D. Lazarevic, G. Germano, P. Stoitzner, , F. Benvenuti

The paper shows that DC-based therapy enhances CD8 T cell responses to neoantigens in lung tumors, particularly in high TMB tumors.

bioRxiv · Jan 26, 2024 · PreprintImmunology

ALCAM-mediated synapses between DC1 and CD8 T cells are inhibited in advanced lung tumors

L. G. Morosi, G. M. Piperno, S. Joshi, R. Amadio, S. Vodret, L. Lopez-Rodriguez, F. Benvenuti

The paper shows that ALCAM-mediated synapses between DC1 and CD8 T cells decrease in advanced lung tumors, impairing immune responses.

bioRxiv · Oct 18, 2023 · PreprintImmunology

Tim4 enables large peritoneal macrophages to cross-present tumor antigens at early stages of tumorigenesis

S. Joshi, L. L. Rodriguez, L. G. Morosi, R. Amadio, M. Pachauri, M. Giacca, G. M. Piperno, F. Benvenuti

This study shows TIM4 enables large peritoneal macrophages to cross-present tumor antigens early in tumorigenesis, promoting CD8 T cell activation and immune surveillance.

bioRxiv · Sep 14, 2023Immunology