Author

L. Hartshorne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. J. P. Simons· 2 shared M. Tatar· 2 shared A. W. McCracken· 1 shared G. Adams· 1 shared J. Thomson· 1 shared S. Trooster· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersPhysiology

M. J. P. Simons

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2 papers

Recent·Most cited

Age-dependent effects of reduced mTor signalling on life expectancy through distinct physiology

M. J. P. Simons, L. Hartshorne, S. Trooster, J. Thomson, M. Tatar

This study shows that reducing mTor signaling in old age decreases mortality, while early transient reduction has long-lasting benefits, suggesting age-dependent effects of mTor on aging.

bioRxiv · Jul 30, 2019 · PreprintPhysiology

The hidden costs of dietary restriction: implications for its evolutionary and mechanistic origins

A. W. McCracken, G. Adams, L. Hartshorne, M. Tatar, M. J. P. Simons

This study tests evolutionary predictions about dietary restriction in Drosophila, finding mortality costs when returning to rich diets after restriction, challenging current evolutionary explanations of DR.

bioRxiv · Apr 8, 2019Evolutionary Biology