Quantitative measurement of activity of JAK-STAT signaling pathways in blood samples and immune cells to predict innate and adaptive cellular immune response to viral infection and accelerate vaccine development.
W. Bouwman, W. Verhaegh, L. Holtzer, A. van de Stolpe
The paper develops mRNA-based tests to quantitatively measure JAK-STAT pathway activity in blood samples to predict immune responses to viral infections and vaccines.
bioRxiv · May 13, 2020 · PreprintImmunology