Author

A. van de Stolpe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 4 Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. van Doorn· 2 shared W. Bouwman· 2 shared W. Verhaegh· 2 shared A. van Brussel· 1 shared C. B. Moelans· 1 shared C. Dam-de Veen· 1 shared E. C. den Biezen-Timmermans· 1 shared F. van Hemert· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCancer Biology

A. van Doorn

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Characterization of immunoactive and immunotolerant CD4+ T cells in breast cancer by measuring activity of signaling pathways that determine immune cell function

Y. Wesseling-Rozendaal, A. van Doorn, K. Willard-Gallo, A. van de Stolpe

The paper measures signaling pathway activity in CD4+ T cells to identify immune tolerant states in breast cancer, finding that Treg cells contribute to immunosuppression and resistance to checkpoint inhibitors.

Cancers · Jan 19, 2022Peer-reviewedCancer Biology

Measuring host immune response status by simultaneous quantitative measurement of activity of signal transduction pathways that coordinate functional activity of immune cells from innate and adaptive immune system

W. Bouwman, W. Verhaegh, A. van Doorn, A. van de Stolpe

The paper develops a method to quantify immune cell signaling pathway activities to assess immune response status in diseases like RA and cancer.

bioRxiv · Oct 6, 2021 · PreprintImmunology

Heterogeneity in signaling pathway activity within primary and between primary and metastatic breast cancer

M. A. Inda, P. van Swinderen, A. van Brussel, C. B. Moelans, W. Veraheagh, H. van Zon, E. C. den Biezen-Timmermans, J. W. Bikker, P. J. van Diest, A. van de Stolpe

This study measures signaling pathway activity in breast cancer samples to assess heterogeneity within primary tumors and between primary and metastatic sites, finding that microscale variation is higher in some pathways and that metastases show less correlation with primary tumors.

Cancers · Mar 16, 2021Peer-reviewedCancer Biology

Quantitative measurement of activity of JAK-STAT signaling pathways in blood samples and immune cells to predict innate and adaptive cellular immune response to viral infection and accelerate vaccine development.

W. Bouwman, W. Verhaegh, L. Holtzer, A. van de Stolpe

The paper develops mRNA-based tests to quantitatively measure JAK-STAT pathway activity in blood samples to predict immune responses to viral infections and vaccines.

bioRxiv · May 13, 2020 · PreprintImmunology

A novel dual antibody staining assay to measure estrogen receptor transcriptional activity

F. van Hemert, C. Dam-de Veen, S. Konings, J. van der Ven, A. van de Stolpe

The paper develops a dual antibody staining assay to better assess estrogen receptor transcriptional activity by measuring the H4624/EP1 fluorescence intensity ratio in nuclear staining.

bioRxiv · Apr 14, 2020Cell Biology