Author

L. Humphrey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Joglekar· 2 shared C. Chen· 2 shared A. Banerjee· 1 shared F. Ferrari· 1 shared J. J. Tyson· 1 shared S. Jema· 1 shared S. Karmarkar· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

A. Joglekar

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2 papers

Recent·Most cited

Signaling protein abundance modulates the strength of the Spindle Assembly Checkpoint

C. Chen, L. Humphrey, S. Jema, S. Karmarkar, F. Ferrari, A. Joglekar

This study shows that the abundance of SAC proteins like Bub1 affects their recruitment to kinetochores and SAC signaling activity, with lower abundance reducing signaling and higher abundance increasing it.

bioRxiv · May 10, 2022 · PreprintCell Biology

BubR1 recruitment to the kinetochore via Bub1 enhances Spindle Assembly Checkpoint signaling

A. Banerjee, C. Chen, L. Humphrey, J. J. Tyson, A. Joglekar

This study shows that Bub1-mediated BubR1 recruitment to kinetochores enhances SAC signaling and reveals BubR1's dual role in SAC activation and silencing.

bioRxiv · Aug 12, 2021Cell Biology