CD73-positive cell spheroid transplantation attenuates colonic atrophy
D. Hisamatsu, N. Itakura, Y. Mabuchi, R. Ozaki, E. G. Suto, Y. Naraoka, A. Ikeda, L. Ito, C. Akazawa
This study shows that transplanting CD73+ mesenchymal stem/stromal cells as spheroids reduces colonic atrophy in colitis by modulating fibroblast activity and extracellular matrix remodeling.
bioRxiv · Aug 23, 2022Cell Biology