Engineered probiotics that sequester arsenite in a mouse gastrointestinal system
Nhu Nguyen, Miaomiao Wang, Sithembio S Msibi, Vincenzo Kennedy, Fateme Esmailie, L. Joseph Su, Lin Li, Clement T. Y. Chan
This paper engineers probiotics to sequester arsenite in the mouse gut, reducing its systemic absorption and demonstrating the feasibility of using living therapeutics for environmental toxin interception.
bioRxiv · Jan 21, 2026 · PreprintSynthetic Biology