Author

L. K. Thompson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 3 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:E. coli· 1 Assay:structural biology· 1

Frequent Co-Authors

S. J. Eyles· 2 shared A. P. K. K. Karunanayake Mudiyanselage· 1 shared K. A. Wahlbeck· 1 shared N. Malik· 1 shared T. Tran· 1 shared X. Li· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 5 mutual co-author links

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2 shared papersBiochemistry

S. J. Eyles

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Author profile →

3 papers

Recent·Most cited

Bacterial chemoreceptor signaling complexes control kinase activity by stabilizing the catalytic domain of CheA

T. Tran, A. P. K. K. Karunanayake Mudiyanselage, S. J. Eyles, L. K. Thompson

This study investigates how bacterial chemoreceptor signaling complexes modulate CheA kinase activity through domain stabilization and destabilization during chemotaxis.

bioRxiv · Oct 28, 2022Biochemistry

Strategies for identifying dynamic regions in protein complexes: flexibility changes accompany methylation in chemotaxis receptor signaling states

N. Malik, K. A. Wahlbeck, L. K. Thompson

This study identifies dynamic regions in bacterial chemoreceptors by comparing methylated and unmethylated states using solid-state NMR, revealing flexibility changes in methylation helices.

Biochimica et Biophysica Acta (BBA) - Biomembranes · Sep 1, 2020Peer-reviewedBiochemistry

Hydrogen exchange of chemoreceptors in functional complexes suggests protein stabilization mediates long-range allosteric coupling

X. Li, S. J. Eyles, L. K. Thompson

This study uses HDX-MS to show that the cytoplasmic domain of bacterial chemoreceptors remains disordered in functional complexes, suggesting that protein stabilization mediates long-range allosteric coupling to control kinase activity.

bioRxiv · Sep 4, 2019Biochemistry