Author

S. J. Eyles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:protein folding & dynamics· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Organism:C. elegans· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:E. coli· 1

Frequent Co-Authors

L. K. Thompson· 2 shared A. P. K. K. Karunanayake Mudiyanselage· 1 shared E. Strieter· 1 shared J. Du· 1 shared J. Fejzo· 1 shared K. K. Deol· 1 shared M. Tonelli· 1 shared P. Chien· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

L. K. Thompson

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Proteomic survey of the DNA damage response in Caulobacter crescentus

T. F. Tashjian, R. D. Zeinert, S. J. Eyles, P. Chien

This study performs a proteomic survey of the DNA damage response in Caulobacter crescentus, identifying novel factors and dynamics not captured by transcriptional studies.

bioRxiv · Mar 24, 2023 · PreprintMicrobiology

Bacterial chemoreceptor signaling complexes control kinase activity by stabilizing the catalytic domain of CheA

T. Tran, A. P. K. K. Karunanayake Mudiyanselage, S. J. Eyles, L. K. Thompson

This study investigates how bacterial chemoreceptor signaling complexes modulate CheA kinase activity through domain stabilization and destabilization during chemotaxis.

bioRxiv · Oct 28, 2022Biochemistry

A Cryptic K48 Ubiquitin Chain Binding Site on UCH37 is Required for its Role in Proteasomal Degradation

J. Du, S. Babik, Y. Li, K. K. Deol, S. J. Eyles, J. Fejzo, M. Tonelli, E. Strieter

bioRxiv · Nov 15, 2021Biochemistry

Hydrogen exchange of chemoreceptors in functional complexes suggests protein stabilization mediates long-range allosteric coupling

X. Li, S. J. Eyles, L. K. Thompson

This study uses HDX-MS to show that the cytoplasmic domain of bacterial chemoreceptors remains disordered in functional complexes, suggesting that protein stabilization mediates long-range allosteric coupling to control kinase activity.

bioRxiv · Sep 4, 2019Biochemistry