Author

L. Le Cam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:transcription & RNA processing· 1

Frequent Co-Authors

O. Radulescu· 2 shared A. Hodgkinson· 1 shared B. Orsetti· 1 shared D. Racoceanu· 1 shared D. Trucu· 1 shared J. Arslan· 1 shared L. Fenou· 1 shared M. Lacroix· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

O. Radulescu

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2 papers

Recent·Most cited

Deciphering Oxygen Distribution and Hypoxia Profiles in the Tumor Microenvironment: A Data-Driven Mechanistic Modeling Approach

P. Kumar, M. Lacroix, P. Dupre, J. Arslan, L. Fenou, B. Orsetti, L. Le Cam, D. Racoceanu, O. Radulescu

The paper develops a data-driven mechanistic model to quantify hypoxia profiles in tumors using reaction-diffusion equations and vascular data.

bioRxiv · Mar 4, 2024Cancer Biology

Spatio-Genetic and Phenotypic Modelling Elucidates Resistance and Re-Sensitisation to Treatment in Heterogeneous Melanoma

A. Hodgkinson, L. Le Cam, D. Trucu, O. Radulescu

This paper models drug resistance and re-sensitisation in melanoma using mathematical frameworks, showing that spatio-genetic heterogeneity and treatment sequencing impact therapeutic outcomes.

bioRxiv · Nov 7, 2018Cancer Biology