Author

L. Fenou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Research Focus:transcription & RNA processing· 1

Frequent Co-Authors

B. Orsetti· 2 shared C. Ribeyre· 1 shared C. Sardet· 1 shared C. Theillet· 1 shared C. Velazquez· 1 shared D. Racoceanu· 1 shared E. Candiello· 1 shared E. Orhan· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

B. Orsetti

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2 papers

Recent·Most cited

Deciphering Oxygen Distribution and Hypoxia Profiles in the Tumor Microenvironment: A Data-Driven Mechanistic Modeling Approach

P. Kumar, M. Lacroix, P. Dupre, J. Arslan, L. Fenou, B. Orsetti, L. Le Cam, D. Racoceanu, O. Radulescu

The paper develops a data-driven mechanistic model to quantify hypoxia profiles in tumors using reaction-diffusion equations and vascular data.

bioRxiv · Mar 4, 2024Cancer Biology

Replication poison treated BRCA1-deficient breast cancers are prone to MRE11 over-resection resulting in single strand DNA accumulation and mitotic catastrophe

I. Tabet, E. Orhan, E. Candiello, L. Fenou, C. Velazquez, B. Orsetti, G. Rodier, W. Jacot, C. Ribeyre, C. Sardet, C. Theillet

This study shows BRCA1-deficient breast cancers are highly sensitive to gemcitabine, leading to ssDNA accumulation and mitotic catastrophe, which may enhance antitumor immune response.

bioRxiv · Oct 31, 2023 · PreprintCancer Biology