IL-6 suppresses vaccine responses in neonatal mice by enhancing IL-2 activity on T follicular helper cells
S. Parvathaneni, J. Yang, L. Lotspeich-Cole, J. Sakai, R. C. Lee, M. Akkoyunlu
This study shows IL-6 suppresses TFH cell responses in neonatal mice by enhancing IL-2 activity, while IL-6 deficiency improves vaccine responses.
bioRxiv · Oct 31, 2022 · PreprintImmunology