Extracellular vesicle microRNA cargo engineering reveals critical mechanisms underlying therapeutic efficacy
L. M. Euscher, K. I. Mentkowski, T. Tarvirdizadeh, I. Julian, K. D. Bhatt, L. A. Eagler, J. K. Lang
This study shows that miRNA cargo is essential for the therapeutic effects of CDC-derived extracellular vesicles in heart disease and identifies a miR cluster that can restore their function.
bioRxiv · Jan 31, 2022 · PreprintBioengineering