Author

J. K. Lang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

K. I. Mentkowski· 2 shared L. A. Eagler· 2 shared R. Zhao· 2 shared T. Tarvirdizadeh· 2 shared A. Lenhard· 1 shared B. Hinz· 1 shared C. A. Manzanero· 1 shared C. Zhou· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersBioengineering

K. I. Mentkowski

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Modeling Mechanical Activation of Macrophages During Pulmonary Fibrogenesis for Targeted Anti-Fibrosis Therapy

Y. Xu, L. Ying, J. K. Lang, B. Hinz, R. Zhao

This study models mechanical activation of macrophages in fibrotic lung tissue and shows pirfenidone inhibits this activation, offering a new mechanism for anti-fibrosis therapy.

bioRxiv · Jul 19, 2023Bioengineering

Neutrophil-driven cardiac damage during invasive Streptococcus pneumoniae infection is regulated by CD73

M. Bhalla, V. R. Ravi, A. Lenhard, E. Y. I. Tchalla, J. K. Lang, E. N. B. Ghanem

This study shows that neutrophils contribute to cardiac damage during pneumococcal infection, with CD73 playing a protective role by regulating extracellular adenosine production.

bioRxiv · Dec 7, 2022 · PreprintImmunology

Surface engineering enhances the therapeutic potential of extracellular vesicles following acute myocardial infarction

K. I. Mentkowski, T. Tarvirdizadeh, C. A. Manzanero, L. A. Eagler, J. K. Lang

This study shows that modifying extracellular vesicles with a cardiomyocyte-targeting peptide improves their cardiac targeting and reduces remote zone apoptosis after myocardial infarction.

bioRxiv · Jan 31, 2022 · PreprintBioengineering

Extracellular vesicle microRNA cargo engineering reveals critical mechanisms underlying therapeutic efficacy

L. M. Euscher, K. I. Mentkowski, T. Tarvirdizadeh, I. Julian, K. D. Bhatt, L. A. Eagler, J. K. Lang

This study shows that miRNA cargo is essential for the therapeutic effects of CDC-derived extracellular vesicles in heart disease and identifies a miR cluster that can restore their function.

bioRxiv · Jan 31, 2022 · PreprintBioengineering

Fast 3D printing of large-scale biocompatible hydrogel models

N. Anandakrishnan, H. Ye, Z. Guo, Z. Chen, K. Mentkowski, J. K. Lang, N. Rajabian, S. Andreadis, Z. Ma, J. Spernyak, J. F. Lovell, D. Wang, J. Xia, C. Zhou, R. Zhao

This paper introduces a fast 3D printing method called FLOAT to create large-scale biocompatible hydrogel models with minimal deformation and cellular injury.

bioRxiv · Oct 22, 2020 · PreprintBioengineering