Clonally expanded CD38hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor-associated arthritis
R. Wang, A. Singaraju, K. E. Marks, L. Shakib, G. S. Dunlap, A. Cunningham-Bussel, L. Chen, A. Tirpack, M. R. Fein, D. J. Todd, L. MacFarlane, S. M. Goodman, E. F. DiCarlo, E. M. Massarotti, J. A. Sparks, , D. A. Rao
This study identifies a distinct CD38hi cytotoxic CD8 T cell subset in ICI-induced arthritis, showing clonal expansion and IFN-driven activation.
bioRxiv · Oct 19, 2021 · PreprintImmunology