Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
15 papers
Recent·Most cited
K. Weinand, S. Sakaue, A. Nathan, A. H. Jonsson, F. Zhang, G. F. M. Watts, Z. Zhu, Accelerating Medicines Partnership Program: RA and SLE Network, D. A. Rao, J. H. Anolik, M. B. Brenner, L. T. Donlin, K. Wei, S. Raychaudhuri
The paper identifies chromatin classes in RA synovial tissue and links them to transcriptional cell states and genetic variants.
bioRxiv · Apr 7, 2023 · PreprintImmunology
G. S. Dunlap, A. Wagner, N. Meednu, F. Zhang, A. H. Jonsson, K. Wei, S. Sakaue, A. Nathan, Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (A, V. P. Bykerk, L. T. Donlin, S. M. Goodman, G. S. Firestein, D. L. Boyle, V. M. Holers, , J. Anolik
This study uses single-cell antigen receptor profiling to identify clonal relationships and functional states of T and B cells in RA synovium.
bioRxiv · Mar 18, 2023 · PreprintImmunology
R. Grieshaber-Bouyer, T. Exner, N. S. Hackert, F. A. Radtke, S. A. Jelinsky, O. Halyabar, A. Wactor, E. Karimizadeh, J. Schettini, A. H. Jonsson, D. A. Rao, L. A. Henderson, C. Mueller-Tidow, H.-M. Lorenz, G. Wabnitz, , P. A. Nigrovic
This study identifies transcriptional and phenotypic changes in synovial fluid neutrophils from arthritis patients, highlighting IFNγ response and aging as key drivers.
bioRxiv · Nov 16, 2021 · PreprintImmunology
T. Sasaki, S. Bracero, J. Keegan, L. Chen, Y. Cao, E. Stevens, Y. Qu, G. Wang, J. Nguyen, S. E. Alves, J. A. Lederer, K. H. Costenbader, D. A. Rao
This study tracks immune cell changes in early systemic lupus erythematosus using mass cytometry and identifies longitudinal shifts in Tfh cells and CXCL10.
bioRxiv · Nov 8, 2021Immunology
G. S. Dunlap, A. C. Billi, F. Ma, M. Maz, L. C. Tsoi, R. Wasikowski, J. E. Gudjonsson, J. M. Kahlenberg, D. A. Rao
This study uses single-cell RNA sequencing to analyze T and NK cells in cutaneous lupus skin and kidney, revealing distinct effector profiles and activation states across tissues.
bioRxiv · Oct 19, 2021Immunology
R. Wang, A. Singaraju, K. E. Marks, L. Shakib, G. S. Dunlap, A. Cunningham-Bussel, L. Chen, A. Tirpack, M. R. Fein, D. J. Todd, L. MacFarlane, S. M. Goodman, E. F. DiCarlo, E. M. Massarotti, J. A. Sparks, , D. A. Rao
This study identifies a distinct CD38hi cytotoxic CD8 T cell subset in ICI-induced arthritis, showing clonal expansion and IFN-driven activation.
bioRxiv · Oct 19, 2021 · PreprintImmunology
K. A. Lagattuta, J. B. Kang, A. Nathan, K. E. Pauken, A. H. Jonsson, D. A. Rao, K. Ishigaki, S. Raychaudhuri
The paper identifies TCR sequence features that influence T cell fate by analyzing TCR sequences from human cells and developing a scoring system for regulatory potential.
bioRxiv · Jun 23, 2021Immunology
M. H. Chang, A. Levescot, N. Nelson-Maney, R. B. Blaustein, K. D. Winden, A. Morris, A. Wactor, S. Balu, R. Grieshaber-Bouyer, K. Wei, L. A. Henderson, Y. Iwakura, R. A. Clark, D. A. Rao, R. C. Fuhlbrigge, P. A. Nigrovic
This study identifies synovial tissue-resident memory T cells as mediators of arthritis flares in murine models and finds a comparable population in human rheumatoid arthritis tissues.
bioRxiv · Jun 4, 2021Immunology
D. P. Simmons, H. Nguyen, E. Gomez-Rivas, Y. Jeong, A. F. Chen, J. K. Lange, G. S. Dyer, P. Blazar, B. E. Earp, A. M. P. RA/SLE Network, D. A. Rao, E. Y. Kim, M. B. Brenner
This study identifies SLAMF7 as a receptor that super-activates macrophages in inflammatory conditions, leading to increased cytokine expression and inflammation.
bioRxiv · Nov 5, 2020 · PreprintImmunology
H.-H. Chang, C.-H. Ho, B. Tomita, A. A. Silva, J. A. Sparks, E. W. Karlson, D. A. Rao, Y. C. Lee, I.-C. Ho
The paper identifies a PTPN22 gene signature in RA patients that can be reversed by targeted therapies and correlates with clinical response.
bioRxiv · Mar 24, 2019Immunology
A. Arazi, D. A. Rao, C. C. Berthier, A. Davidson, Y. Liu, P. J. Hoover, A. Chicoine, T. M. Eisenhaure, A. H. Jonsson, S. Li, D. J. Lieb, E. P. Browne, A. Noma, D. Sutherby, S. Steelman, , B. Diamond
This study uses single-cell RNA-seq to analyze immune cell subsets in lupus nephritis kidneys, identifying pro-inflammatory and resolving responses and potential therapeutic targets.
bioRxiv · Jul 7, 2018Immunology
F. Zhang, K. Wei, K. Slowikowski, C. Y. Fonseka, D. A. Rao, S. Kelly, S. M. Goodman, D. Tabechian, L. B. Hughes, K. Salomon-Escoto, G. F. M. Watts, W. Apruzzese, D. J. Lieb, D. L. Boyle, A. M. Mandelin, , S. Raychaudhuri
The paper identifies key inflammatory cell states in RA synovial tissues using integrated single-cell and mass cytometry data from patient samples.
bioRxiv · Jun 20, 2018Immunology
L. T. Donlin, D. A. Rao, K. Wei, K. Slowikowski, M. J. McGeachy, J. D. Turner, N. Meednu, F. Mizoguchi, M. Gutierrez-Arcelus, D. J. Lieb, J. Keegan, K. Muskat, J. Hillman, C. Rozo, E. Ricker, , M. B Brenner
This paper establishes a protocol for dissociating cryopreserved synovial tissue to obtain viable cells with preserved transcriptomes and surface markers, enabling high-dimensional analysis of rheumatoid arthritis pathology.
bioRxiv · Mar 19, 2018Immunology
M. Reyes, D. Vickers, K. Billman, T. Eisenhaure, P. Hoover, E. Browne, D. A. Rao, N. Hacohen, P. C. Blainey
This paper presents a microfluidic system for sorting and profiling immune cell subsets using RNA-seq, demonstrating its utility in identifying cell-specific disease signatures in lupus patients.
bioRxiv · Feb 7, 2018Bioengineering
F. Mizoguchi, K. Slowikowski, J. L. Marshall, K. Wei, D. A. Rao, S. K. Chang, H. N. Nguyen, E. H. Noss, J. D. Turner, B. E. Earp, P. E. Blazar, J. Wright, B. P. Simmons, L. T. Donlin, G. D. Kalliolias, , M. B. Brenner
The paper identifies disease-associated fibroblast subsets in rheumatoid arthritis using single-cell transcriptomics and flow cytometry, revealing subset-specific markers and functional differences.
bioRxiv · May 26, 2017Immunology