J. A. Sparks

Glycome profiling and immunohistochemistry uncover spaceflight-induced changes in non-cellulosic cell wall components in Arabidopsis thaliana seedling roots

Polyfunctional IL-17A+ MAIT cells are expanded in the peripheral blood of patients with HLA-B27+ axial spondyloarthritis

This study identifies an expansion of polyfunctional IL-17A+ MAIT cells in HLA-B27+ axSpA patients, linking intestinal inflammation to axial spondyloarthritis pathogenesis.

Clonally expanded CD38hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor-associated arthritis

This study identifies a distinct CD38hi cytotoxic CD8 T cell subset in ICI-induced arthritis, showing clonal expansion and IFN-driven activation.

Spatial and Temporal Localization of SPIRRIG and WAVE/SCAR Reveal Roles for These Proteins in Actin-Mediated Root Hair Development

This study identifies the spatial and temporal roles of SPIRRIG and WAVE/SCAR proteins in actin-mediated root hair development through localization analysis and functional assays.

Utilizing a PTPN22 gene signature to predict response to targeted therapies in rheumatoid arthritis

The paper identifies a PTPN22 gene signature in RA patients that can be reversed by targeted therapies and correlates with clinical response.