Reproductive history determines ErbB2 locus amplification, WNT signalling and tumour phenotype in a murine breast cancer model
L. D. Ordonez, L. Melchor, K. R. Greenow, H. Kendrick, G. Tornillo, J. Bradford, P. Giles, M. J. Smalley
The paper shows that reproductive history influences HER2-driven breast cancer tumour subtypes through locus amplification and WNT signalling activation in a mouse model.
bioRxiv · Oct 30, 2020Cancer Biology