Colloidal aggregation confounds cell-based Covid-19 antiviral screens
I. S. Glenn, L. N. Hall, M. M. Khalid, M. Ott, B. K. Shoichet
The paper investigates how colloidal aggregation affects cell-based antiviral screens for Covid-19 drugs, finding that aggregation reduces antiviral potency and suggests a non-specific mechanism.
bioRxiv · Oct 27, 2023Biochemistry