BiochemistrybioRxivPreprint
New Structure of Class II Fructose-1,6-Bisphosphatase from Francisella tularensis suggest a novel catalytic mechanism for the entire class
C. Abad-Zapatero, A. I. Selezneva, L. N. M. Harding…·F. Movahedzadeh
The paper presents crystal structures of FBPaseII from Francisella tularensis and Mycobacterium tuberculosis, revealing a revised catalytic mechanism involving a positive dipole rather than a metal cofactor for phosphate retention.
DOI 10.1101/2022.09.05.506711