Recurring EPHB1 mutations in human cancers alter receptor signalling and compartmentalisation of colorectal cancer cells
S. Kundu, L. Nunes, J. Adler, L. Mathot, I. Stoimenov, T. Sjoblom
This study identifies recurring EPHB1 mutations in cancers, showing some impair cell compartmentalisation while others enhance it, with functional consequences on signalling pathways.
bioRxiv · Mar 18, 2023Cancer Biology