Author

L. Orchard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:plant (other)· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. Llinas· 3 shared E. Yeh· 1 shared G. A. Josling· 1 shared H. J. Painter· 1 shared H. Painter· 1 shared J. E. Gisselberg· 1 shared J. Niemand· 1 shared J. Reader· 1 shared

Activity by Year

2017-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersMicrobiology

M. Llinas

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Hierarchical transcriptional control regulates Plasmodium falciparum sexual differentiation

R. van Biljon, R. van Wyk, H. Painter, L. Orchard, J. Reader, J. Niemand, M. Llinas, L.-M. Birkholtz

This study provides a high-resolution transcriptome of Plasmodium falciparum during gametocytogenesis, revealing dynamic gene expression shifts and transcriptional control mechanisms.

bioRxiv · Jun 7, 2019Biochemistry

Regulation of sexual differentiation is linked to invasion in malaria parasites

G. A. Josling, J. Venezia, L. Orchard, T. J. Russell, H. J. Painter, M. Llinas

The paper shows PfAP2-G activates gametocyte genes and also promotes red blood cell invasion genes, linking sexual differentiation to invasion in malaria parasites.

bioRxiv · Feb 8, 2019 · PreprintMicrobiology

A Specific Non-Bisphosphonate Inhibitor Of The Bifunctional Farnesyl/Geranylgeranyl Diphosphate Synthase In Malaria Parasites

J. E. Gisselberg, Z. Herrera, L. Orchard, M. Llinas, E. Yeh

This paper identifies MMV019313 as a specific non-bisphosphonate inhibitor of PfFPPS/GGPPS in malaria parasites, showing superior properties and selectivity over bisphosphonates.

bioRxiv · Jul 21, 2017Microbiology