Author

L. Palmqvist

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1

Frequent Co-Authors

A. Waraky· 2 shared C. Plass· 2 shared D. Weichenhan· 2 shared J. Adamsson· 2 shared J. Hey· 2 shared M. Baehr· 2 shared P. Lutsik· 2 shared A. Ashouri· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

A. Waraky

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Altered enhancer-promoter interaction leads to MNX1 expression in pediatric acute myeloid leukemia with t(7;12)(q36;p13)

D. Weichenhan, A. Riedel, E. Sollier, U. H. Toprak, J. Hey, K. Breuer, J. A. Wierzbinska, A. Touzart, P. Lutsik, M. Baehr, A. Oestlund, C. Nilsson, S. Jacobsson, M. Edler, A. Waraky, , C. Plass

The paper shows MNX1 overexpression in t(7;12)(q36;p13) AML is due to enhancer hijacking, not oncofusion, and is common in pediatric cases.

bioRxiv · Sep 13, 2023 · PreprintCancer Biology

Reduced mitochondrial transcription sensitizes acute myeloid leukemia cells to BCL-2 inhibition

L. S. Arabanian, J. Adamsson, A. Unger, R. Di Lucrezia, T. Bergbrede, A. Ashouri, E. Larsson, P. Nussbaumer, B. M. Klebl, L. Palmqvist, C. M. Gustafsson

This study shows that inhibiting mitochondrial transcription with IMT sensitizes acute myeloid leukemia cells to BCL-2 inhibition, enhancing apoptosis and survival in mouse models.

bioRxiv · Sep 23, 2022 · PreprintCancer Biology

Aberrant MNX1 Expression Associated with t(7;12)(q36;p13) Pediatric Acute Myeloid 1 Leukemia Induces the Disease Through Altering Histone Methylation

A. Waraky, A. Ostlund, T. Nilsson, D. Weichenhan, P. Lutsik, M. Baehr, J. Hey, J. Adamsson, M. H. A. Morsy, S. Li, L. Fogelstrand, C. Plass, L. Palmqvist

This study identifies MNX1 as a driver of t(7;12)(q36;p13) pediatric AML by altering histone methylation and shows that targeting MNX1 can prevent leukemia development.

bioRxiv · Jun 10, 2022Cancer Biology